Cephradine
CAS number:
38821-53-3
Molecular formula:
C16H19N3O4S
molecular weight:
349.4048
Chemical structure:
Details
Product Name
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Cefradine
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Shelf Life
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2 years
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Tests
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BP2012 Specifications
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Results
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Appearance
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White or slightly yellow powder,hygroscopic powder.
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White powder,
hygroscopic powder.
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Solubility
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Slightly soluble in water,practically insoluble in ethanol 96 percent and in hexane.
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Conform
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Identification
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IR spectrum should match with that of standard
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Conform
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Clarity of solution
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Solution S is not more opalescent than reference suspension II
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Conform
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Absorbance at 450nm
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Not more than 0.6
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0.3
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pH
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Between 3.0 and 6.0
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4.7
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Specific optical rotation
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Between +80.0°and +90.0°(anhydrous substance)
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+85°
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Related substances
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|
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Impurity B
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Maximum0.25%
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<0.25%
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Impurities A, C, D, E, F, G
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Maximum0.25%
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<0.25%
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Any other impurity
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Maximum0.5%
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<0.5%
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Total impurity
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Maximum2.0%
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<2.0%
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N,N-Dimethylaniline
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Maximum 20 ppm
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Not used in process
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Water
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Maximum 6.0%,determined on 0.300 g.
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4.3%
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Sulphated ash
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Maximum 0.2%
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<0.1%
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Assay
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|
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cefradine
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Minimum 90.0%
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96.8%
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cefalexin
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Maximum 5.0%
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1.5%
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4′,5′-dihydrocefradine
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Maximum 2.0 %
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1.0%
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Sum of cefradine, cefalexin and 4′,5′-dihydrocefradine
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Minimum 96.0%.and maximum 102.0%(anhydrous substance)
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99.3%
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